Disease: Familial multiple trichoepitheliomata
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WIF1 Q9Y5W5 WNT inhibitory factor 1 Calcium-binding protein 1.3E-09 0.507 0.731
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TFF1 P04155 trefoil factor 1 Signaling 8.9E-04 0.529 0.769
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
RUNX3 Q13761 RUNX family transcription factor 3 Transcription factor 0.84 0.459 0.731
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846
MUC6 Q6W4X9 mucin 6, oligomeric mucus/gel-forming Enzyme modulator 2.2E-39 0.559 0.615
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MIR31 microRNA 31 0.471 0.769
MIR21 microRNA 21 0.363 0.846